GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| UVM | cis | rs10935120 | 1 | rs7645295 | chr3:134307734 | ANAPC13 | chr3:134196547-134204865:- | 0.45 | 6.73 | 1.03E-8 | Height |
| UVM | cis | rs3919627 | 1 | rs7647523 | chr3:42887055 | VIPR1 | chr3:42544104-42579065:+ | -0.63 | -4.73 | 1.63E-5 | Obesity-related traits |
| UVM | cis | rs10935120 | 1 | rs7648990 | chr3:134244390 | ANAPC13 | chr3:134196547-134204865:- | 0.46 | 6.87 | 6.1E-9 | Height |
| UVM | cis | rs9876781 | 1 | rs7651407 | chr3:48443816 | TREX1 | chr3:48501186-48509043:+ | -0.39 | -4.95 | 7.49E-6 | Longevity |
| UVM | cis | rs9876781 | 1 | rs7653691 | chr3:48419689 | TREX1 | chr3:48501186-48509043:+ | 0.42 | 4.99 | 6.38E-6 | Longevity |
| UVM | cis | rs76935404 | 1 | rs76935404 | chr19:41419294 | CYP2B7P1 | chr19:41430170-41456563:+ | -0.68 | -5.42 | 1.37E-6 | nicotine metabolite ratio in current smokers |
| UVM | cis | rs78153629 | 1 | rs76994419 | chr15:40714150 | C15orf23 | chr15:40674922-40686488:+ | 0.91 | 5.13 | 3.95E-6 | Heschl's gyrus morphology |
| UVM | cis | rs7705093 | 1 | rs7705093 | chr5:96290647 | ERAP2 | chr5:96211644-96255398:+ | 0.93 | 7.65 | 3.27E-10 | Birdshot chorioretinopathy |
| UVM | cis | rs78153629 | 1 | rs77531164 | chr15:40673466 | C15orf23 | chr15:40674922-40686488:+ | 0.93 | 6.05 | 1.34E-7 | Heschl's gyrus morphology |
| UVM | cis | rs78153629 | 1 | rs78153629 | chr15:40673465 | C15orf23 | chr15:40674922-40686488:+ | 0.93 | 6.05 | 1.34E-7 | Heschl's gyrus morphology |
| UVM | cis | rs2071518 | 1 | rs7839760 | chr8:120421534 | NOV | chr8:120428552-120436678:+ | 0.57 | 4.78 | 1.35E-5 | Blood pressure |
| UVM | cis | rs78153629 | 1 | rs78604110 | chr15:40681854 | C15orf23 | chr15:40674922-40686488:+ | 0.9 | 5.65 | 5.93E-7 | Heschl's gyrus morphology |
| UVM | cis | rs78153629 | 1 | rs79044944 | chr15:40676285 | C15orf23 | chr15:40674922-40686488:+ | 0.9 | 5.65 | 5.93E-7 | Heschl's gyrus morphology |
| UVM | cis | rs11190604 | 1 | rs7905961 | chr10:102297391 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs7973719 | 1 | rs7973719 | chr12:7334813 | PEX5 | chr12:7341759-7371167:+ | 0.74 | 10.3 | 1.94E-14 | IgG glycosylation |